Polymyxin B and rifampin: new regimen for multiresistant Serratia marcescens infections.

نویسندگان

  • R C Ostenson
  • B T Fields
  • C M Nolan
چکیده

Polymyxin B and rifampin were given to 12 patients with multi-drug-resistant nosocomial Serratia marcescens infections. Eight cures were achieved; drug hepatotoxicity occurred once; one fatal suprainfection was encountered; and two patients died during therapy of causes related to severe underlying illnesses. Polymyxin B and rifampin were uniformly synergistic in vitro against the infecting strains and against 40 additional clinical isolates of S. marcescens.

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منابع مشابه

In vitro additive effect of polymxin B and rifampin against Serratia marcesen.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 12 6  شماره 

صفحات  -

تاریخ انتشار 1977